Rabbit Polyclonal antibody to MPP5 (membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5))Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains (Tseng et al., 2001 [PubMed 11311936]). MPP5 is a member of the p55-like MAGUK subfamily.[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human MPP5. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
Human
Predicted Reactivity
Mouse, Rat, Xenopus laevis, Chicken, BovineMouse (94%), Rat (95%), Xenopus laevis (85%), Chicken (85%), Bovine (96%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
FLJ12615 antibody, PALS1 antibody, MPP5 antibody, stardust antibody, MAGUK p55 subfamily member 5 antibody, "membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) antibody"
Molecular Weight(MW)
77 kDa (note) (2)
Cellular Localization
Cell membrane; Peripheral membrane protein , Endomembrane system; Peripheral membrane protein , Cell junction , tight junction
Application
Application
Sample (30 ug of whole cell lysate) A: NT2D1 B: U87-MG C: SK-N-SH 7.5% SDS PAGE diluted at 1:1000
Positive Control
NT2D1 , U87-MG , SK-N-SH
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.