| Product Name | MSK1 (phospho Thr581) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to MSK1 ( phospho T581 )MSK 1, a Mitogen and Stress activated protein Kinase, is activated by ERK as well as p38 MAPK in response to growth factors and various cellular stress stimuli. MSK 1 resembles RSK by having two kinase domains connected by a regulator linker region. Phosphorylation of RSK 1 at Ser 364, Ser381 and Thr574 is critical for RSK 1 activity. These sites are analogous to Ser360, Ser376 and Thr581 of MSK 1 and maybe important for MSK 1 activity as well. |
| Immunogen | Available on request. |
| Modification | p-Thr581 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: Use at a concentration of 1 - 2 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | RLPK MSPK1 9252 MGC1911 603607 MSK1 O75582 RPS6KA5 MSK1 (phospho T581) MSK1 (phospho Thr581) MSK1 (pT581) MSK1 (pThr581) MSK1 phospho T581 MSK1 phospho Thr581 Phospho MSK1 (T581) Phospho MSK1 (Thr581) Phospho MSK1 (pT581) Phospho MSK1 (pTh |
|---|---|
| Target | MSK1 |
| Tissue Specificity | This antibody detects 90 kDa MSK 1 only when phosphorylated at Thr581. It does not cross-react with non-phosphorylated MSK 1, or MSK 1 phosphorylated at other sites. It does not cross-react with RSK 1, RSK 2 or RSK 3. |
| Application Notes | WB: Use at a concentration of 1 - 2 μg/ml. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | PBS pH7.2 with 50% glycerol, 1% BSA and 0.02% sodium azide |
