Rabbit polyclonal antibody to PID/MTA2PID/MTA2, also termed MTA1-L1, is a novel molecule that has been found to be involved in p53 pathway. PID/MTA2 modulates the enzymatic activity of the histone deacetylase complex and its expression reduces the levels of acetylated p53. Deacetylastion of p53 by PID/MTA2 represses p53-dependent transcriptional activation and modulates p53-mediated cell growth arrest and apoptosis. PID/MTA2 is ubiquitously expressed in human tissues.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
Western blotting (1 µg/ml). An approximately 75 kDa band can be detected. HeLa cell lysate can be used as a positive control. No cross-reactivity to MTA1.:
Species Reactivity
HumanMouseRat
Concentration
0.5mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
MTA1L1 PID MTA2 MTA1-L1 DKFZp686F2281 MTA1 L1
Target
PID/MTA2
Tissue Specificity
This antibody is specific for PID/MTA2.
Application Notes
Western blotting (1 µg/ml). An approximately 75 kDa band can be detected. HeLa cell lysate can be used as a positive control. No cross-reactivity to MTA1.:
Additional Information
Form
Liquid
Storage Instructions
The antibody solution should be gently mixed before use. Stored at -20 °C for future use.