Application
MTBP antibody [N1N3] detects MTBP protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. MTBP antibody [N1N3] dilution: 1:500.Application
Sample (30 ug of whole cell lysate) A: Jurkat B: THP-1 C: HL-60 5% SDS PAGE diluted at 1:1000| Product Name | MTBP antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to MTBP (Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa)Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent TP53/p53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of TP53/p53 and its subsequent degradation. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human MTBP. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, BovineMouse (81%), Bovine (89%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MDM2BP antibody MTBP antibody hMTBP antibody mdm2-binding protein antibody "MDM2 (mouse double minute 2)-binding protein 104kD antibody" "Mdm2 transformed 3T3 cell double minute 2 p53 binding protein (mouse) binding protein 104kDa antibody" |
|---|---|
| Molecular Weight(MW) | 102 kDa (note) (2) |
Application
MTBP antibody [N1N3] detects MTBP protein at cytoplasm on human colon carcinoma by immunohistochemical analysis. Sample: Paraffin-embedded colon carcinoma. MTBP antibody [N1N3] dilution: 1:500.
Application
Sample (30 ug of whole cell lysate) A: Jurkat B: THP-1 C: HL-60 5% SDS PAGE diluted at 1:1000| Positive Control | Jurkat , THP-1 , HL-60 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
