Application
Western blot analysis of TFAM in rat kidney tissue lysate.| Product Name | mtTFA antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to mtTFATranscription factor A mitochondria (TFAM) is an important activator of mitochondrial DNA transcription and replication. Studies in mice have shown that TFAM is required to regulate the mitochondrial genome copy number and is important for embryonic development. TFAM has been associated with mitochondrial disorder which includes ocular myopathy and muscular wasting in humans. Kearns-Sayre syndrome was shown in mouse model when expression of the gene was eliminated by targeted disruption in heart and muscle cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| Western blotting (0.5-4µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 27 kDa band from rat kidney tissue lysate. Reactivity to other species has not been tested.: |
|
| Species Reactivity | Rat |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | MtTF1 Transcription factor A mtTFA TCF6 TCF6L2 |
|---|---|
| Target | TFAM |
| Tissue Specificity | This antibody is specific for mtTFA. |
Application
Western blot analysis of TFAM in rat kidney tissue lysate.| Application Notes | Western blotting (0.5-4µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 27 kDa band from rat kidney tissue lysate. Reactivity to other species has not been tested.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20ºC. Avoid multiple freeze-thaw cycles.The antibody solution should be gently mixed before use. |
| Storage Buffer | PBS (pH 7.2) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal |
