Application
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using MYT1 (Ab-83) Antibody. The picture on the right is treated with the synthesized peptide.Application
Western blot analysis of extracts from HeLa cells, using MYT1 (Ab-83) Antibody. The lane on the right is treated with the synthesized peptide.| Product Name | MYT1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to MYT1Acts as a negative regulator of entry into mitosis (G2 to M transition) by phosphorylation of the CDK1 kinase specifically when CDK1 is complexed to cyclins. Mediates phosphorylation of CDK1 predominantly on 'Thr-14'. Also involved in Golgi fragmentation. May be involved in phosphorylation of CDK1 on 'Tyr-15' to a lesser degree, however tyrosine kinase activity is unclear and may be indirect. May be a downstream target of Notch signaling pathway during eye development. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PKMYT1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIHC-PWB |
| IHC: 1:50~1:100 : |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase Myt1 kinase MYT1 EC=2.7.11.1 PKMYT1 Membraneassociated tyrosine and threoninespecific cdc2inhibitory kinase |
|---|---|
| Target | MYT1 |
| Molecular Weight(MW) | 54 kDa (note) |
| Tissue Specificity | MYT1 (Ab-83) Antibody detects endogenous levels of total MYT1 protein. |
Application
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using MYT1 (Ab-83) Antibody. The picture on the right is treated with the synthesized peptide.
Application
Western blot analysis of extracts from HeLa cells, using MYT1 (Ab-83) Antibody. The lane on the right is treated with the synthesized peptide.| Application Notes | IHC: 1:50~1:100 : |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at -20 degrees Celcius. Product is stable for at least 1 year. |
| Storage Buffer | Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 79% glycerol. |
