Rabbit Polyclonal antibody to NALP2 (NLR family, pyrin domain containing 2)NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]
Immunogen
Recombinant protein encompassing a sequence within the center region of human NALP2. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFWB
*Optimal dilutions/concentrations should be determined by the researcher.
:
Species Reactivity
Human
Predicted Reactivity
Rhesus MonkeyRhesus Monkey (82%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
CLR19.9 antibody FLJ20510 antibody NALP2 antibody NBS1 antibody PAN1 antibody PYPAF2 antibody NLRP2 antibody nucleotide-binding site protein 1 antibody "nucleotide-binding oligomerization domain leucine rich repeat and pyrin domain containing 2 an
Molecular Weight(MW)
121 kDa (note) (4)
Application
Application
Immunofluorescence analysis of methanol-fixed HeLa, using NALP2 antibody at 1:200 dilution.
Application
Sample (30 ug of whole cell lysate) A: A431 7.5% SDS PAGE diluted at 1:10000
Positive Control
A431 , H1299 , HeLa , Molt-4
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.