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Nav1.1 antibody

Catalog Number:OM264660
OM264660
Discount Price
OM264660-100ul
1~2 Week
100ul
OM264660-50ul
50ul
OM264660-20ul
20ul
1~2 Week
Product Profile
Product Name Nav1.1 antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to Nav1.1has voltage gated sodium ion channel activity; plays a role in generation of action potential [RGD, Feb 2006]
Immunogen Peptide TEEQKKYYNAMKKLGSKK(C), corresponding to amino acid residues 1501-1518 of rat Nav1.1 (Accession P04774). Intracellular loop between domains III and IV.
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications ICC/IFIHCIPWB
ICC/IF:1:200~1:500
IHC:1:50~1:200
IP:1:100~1:500
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity HumanMouseRat
Concentration 1mg/ml
Purification Affinity purified
Target Information
Gene Synonyms sodium channel
voltage-gated
type I
alpha
Scn1a
Target Nav1.1
Application

Application

Anti-Pan_NaV - Western blot analysis of rat brain membranes: 1. Anti-Pan Nav antibody, (1:200). 2. Anti-Pan Nav antibody, preincubated with the control peptide antigen.

Application

Anti-Pan_NaV - Expression of Nav channels in rat cerebellum Immunohistochemical staining of rat cerebellum using Anti-Pan Nav antibody. A. Nav channels (red) appear in Purkinje cell bodies (vertical arrows) and in cells of the molecular layer (Mol), (horizontal arrows). B. Staining of Parvalbumin (green) in the same brain section. C. Confocal merge of Nav channels and Parvalbumin demonstrates the location of Nav channels to the cell body of Purkinje neurons.
Application Notes ICC/IF:1:200~1:500
IHC:1:50~1:200
IP:1:100~1:500
WB:1:500~1:2000
Notes:Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form Liquid
Storage Instructions Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.05% NaN3.
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