Application
Western blot analysis of Nibrin (pS343) expression in Jurkat (A); LO2 UV-treated (B); Raw264.7 UV-treated (C); PC12 (D) whole cell lysates.| Product Name | NBS1 (phospho Ser343) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NBS1 (phospho Ser343)Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Nibrin (pS343). The exact sequence is proprietary. |
| Modification | p-Ser343 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | AT-V2 NBS1 NBS NBN ATV nibrin AT-V1 P95 |
|---|---|
| Target | NBS1 (phospho Ser343) |
| Tissue Specificity | Recognizes endogenous levels of Nibrin (pS343) protein. |
Application
Western blot analysis of Nibrin (pS343) expression in Jurkat (A); LO2 UV-treated (B); Raw264.7 UV-treated (C); PC12 (D) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide. |
