Rabbit polyclonal to N CadherinThis gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Immunogen
Synthetic peptide representing amino acids 808-827 (RMDERPIHAEPQYPVRSAAP) of human N-Cadherin.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-FIHC-PWB
IHC-P: Use at a concentration of 5 - 10 μg/ml. IHC-Fr: Use at a concentration of 5 - 10 μg/ml. WB: Use at a concentration of 5 - 10 μg/ml. Use under non reducing and non-heating conditions. Predicted molecular weight: 99.9 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouseBovine
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Target Information
Gene Synonyms
N Cadherin 114020 P19022 CDHN NCAD 1000 CDH2
Target
N Cadherin
Tissue Specificity
This antibody does not react with human E or P Cadherin. It does not inhibit N Cadherin dependent cell-cell contact.
Application Notes
IHC-P: Use at a concentration of 5 - 10 μg/ml. IHC-Fr: Use at a concentration of 5 - 10 μg/ml. WB: Use at a concentration of 5 - 10 μg/ml. Use under non reducing and non-heating conditions. Predicted molecular weight: 99.9 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.