Application
Neuroserpin antibody [N1C1] detects Neuroserpin protein at on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. Neuroserpin antibody [N1C1] dilution: 1:500.Application
Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE diluted at 1:500Application
Sample (30 ug of whole cell lysate) A: 293T B: Molt-4 10% SDS PAGE diluted at 1:1000| Product Name | Neuroserpin antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to Neuroserpin (serpin peptidase inhibitor, clade I (neuroserpin), member 1)This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human Neuroserpin. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | HumanMouse |
| Predicted Reactivity | Rat, Rhesus Monkey, BovineRat (85%), Rhesus Monkey (96%), Bovine (88%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | DKFZp781N13156 antibody PI12 antibody neuroserpin antibody SERPINI1 antibody PI-12 antibody peptidase inhibitor 12 antibody serpin I1 antibody "serine (or cysteine) proteinase inhibitor clade I (neuroserpin) member 1 antibody" "serpin peptidase i |
|---|---|
| Molecular Weight(MW) | 46 kDa (note) (3) |
| Cellular Localization | Secreted |
Application
Neuroserpin antibody [N1C1] detects Neuroserpin protein at on mouse fore brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse fore brain. Neuroserpin antibody [N1C1] dilution: 1:500.
Application
Sample (50 ug of whole cell lysate) A: mouse brain 10% SDS PAGE diluted at 1:500
Application
Sample (30 ug of whole cell lysate) A: 293T B: Molt-4 10% SDS PAGE diluted at 1:1000| Positive Control | 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
