Rabbit polyclonal antibody to NIPSNAP3BThe NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. While NIPSNAP3B is highly expressed skeletal muscle, NIPSNAP3A mRNA levels are low. NIPSNAP proteins have been suggested to be important in vesicular transport. NIPSNAP3B antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHC-PWB
IHC-P:1:50~1:200 WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
NIPSNAP3B Non-neuronal SNAP25-like protein 3B Nonneuronal SNAP25like protein3B Nonneuronal SNAP25like protein 3B NIPSNAP3
Target
NIPSNAP3B
Tissue Specificity
This antibody is specific for NIPSNAP3B
Application
Application
Immunohistochemistry of NIPSNAP3B in mouse brain tissue with NIPSNAP3B antibody at 2.5 ug/ml.
Application
Western blot analysis of NIPSNAP3B in mouse brain tissue lysate with NIPSNAP3B antibody at (A) 1 and (B) 2 ug/ml.