Application
IHC-P analysis of human nasopharyngeal carcinoma using NKG2D antibody at a dilution of 1:200.| Product Name | NKG2D antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NKG2DNatural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NK cells preferentially express several calcium-dependent (C-type) lectins, which have been implicated in the regulation of NK cell function. The NKG2 gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed in NK cells. This gene encodes a member of the NKG2 family. The encoded transmembrane protein is characterized by a type II membrane orientation (has an extracellular C terminus) and the presence of a C-type lectin domain. It binds to a diverse family of ligands that include MHC class I chain-related A and B proteins and UL-16 binding proteins, where ligand-receptor interactions can result in the activation of NK and T cells. The surface expression of these ligands is important for the recognition of stressed ce |
| Immunogen | KLH conjugated synthetic peptide derived from human NKG2D C-terminus |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-P |
| IHC-P(1:100-500): |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | KLR KLRK1 NKG2-D killer cell lectin-like receptor subfamily K member 1 CD314 D12S2489E |
|---|---|
| Target | NKG2D |
| Tissue Specificity | NKG2D/CD314/KLRK1 |
Application
IHC-P analysis of human nasopharyngeal carcinoma using NKG2D antibody at a dilution of 1:200.| Application Notes | IHC-P(1:100-500): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and less than 0.09% sodium azide. |
