Application
Western blot analysis of NR2B (pY1474) expression in HEK293T UV-treated (A); mouse brain (B); rat brain (C) whole cell lysates.| Product Name | NMDAR2B (phospho Tyr1474) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NR2B (phospho Tyr1474)N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NMDAR2B. The exact sequence is proprietary. |
| Modification | p-Tyr1474 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | NR2B GRIN2B NMDAR2B EIEE27 GluN2B glutamate receptor ionotropic N-methyl D-aspartate 2B hNR3 MRD6 |
|---|---|
| Target | NR2B |
| Tissue Specificity | Recognizes endogenous levels of NMDAR2B (pY1474) protein. |
Application
Western blot analysis of NR2B (pY1474) expression in HEK293T UV-treated (A); mouse brain (B); rat brain (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
