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nNOS (phospho Ser852) antibody

Catalog Number:OM265656
OM265656
Discount Price
OM265656-100ul
1~2 Week
100ul
OM265656-50ul
50ul
OM265656-20ul
20ul
1~2 Week
Product Profile
Product Name nNOS (phospho Ser852) antibody
Antibody Type Primary Antibodies
Product description Rabbit Polyclonal antibody to nNOS (phospho Ser852)The protein encoded by this gene belongs to the family of nitric oxide synthases, which synthesize nitric oxide from L-arginine. Nitric oxide is a reactive free radical, which acts as a biologic mediator in several processes, including neurotransmission, and antimicrobial and antitumoral activities. In the brain and peripheral nervous system, nitric oxide displays many properties of a neurotransmitter, and has been implicated in neurotoxicity associated with stroke and neurodegenerative diseases, neural regulation of smooth muscle, including peristalsis, and penile erection. This protein is ubiquitously expressed, with high level of expression in skeletal muscle. Multiple transcript variants that differ in the 5' UTR have been described for this gene but the full-length nature of these transcripts is not known. Additionally, alternatively spliced transcript variants encoding different isoforms (some testis-specific) have been found for this gene.[provided by RefSeq, Feb 2011]
Immunogen Peptide sequence around phosphorylation site of serine 852(F-N-S(p)-V-S) derived from Human n-NOS .
Modification p-Ser852
Key Feature
Clonality Polyclonal
Isotype IgG
Host Species Rabbit
Tested Applications WB
WB: 1:500 - 1:1000:
Species Reactivity HumanMouseRat
Concentration 1mg/ml (Please refer to the vial label for the specific concentration)
Purification Affinity purified
Target Information
Gene Synonyms nitric oxide synthase 1 (neuronal)
IHPS1
NOS
NOS1
NC-NOS
nNOS
bNOS
N-NOS
Target nNOS (phospho Ser852)
Tissue Specificity The antibody detects endogenous level of n-NOS only when phosphorylated at serine 852.
Application

Application

Western blot analysis of extracts from A549 tissue using n-NOS (Phospho-Ser852) antibody. The lane on the right is treated with the antigen-specific peptide.
Application Notes WB: 1:500 - 1:1000:
Additional Information
Form Liquid
Storage Instructions Store at -20˚C/1 year
Storage Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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