Rabbit Polyclonal antibody to NR2C2Members of the nuclear hormone receptor family, such as NR2C2, act as ligand-activated transcription factors. The proteins have an N-terminal transactivation domain, a central DNA-binding domain with 2 zinc fingers, and a ligand-binding domain at the C terminus. The activated receptor/ligand complex is translocated to the nucleus where it binds to hormone response elements of target genes (Yoshikawa et al., 1996 [PubMed 8661150]).[supplied by OMIM, Mar 2008]
Immunogen
Recombinant protein of human NR2C2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Species Reactivity
HumanRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
TR4 TAK1 nuclear receptor subfamily 2 group C member 2 hTAK1 TR2R1
Target
NR2C2
Molecular Weight(MW)
65 kDa (note)
Application
Application
WB analysis of extracts from various cells using NR2C2 antibody.
Application Notes
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.