| Product Name | NSMase2 antibody [C1C3] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to NSMase2 (sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II))Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human NSMase2. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Predicted Reactivity | Human, Mouse, Rat, BovineHuman (100%), Mouse (88%), Rat (89%), Bovine (87%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FLJ22593 antibody, MGC138443 antibody, NSMASE2 antibody, SMPD3 antibody, neutral sphingomyelinase 2 antibody, sphingomyelin phosphodiesterase 3 antibody, nSMase-2 antibody, neutral sphingomyelinase II antibody, "sphingomyelin phosphodiesterase 3, neutral m |
|---|---|
| Molecular Weight(MW) | 71 kDa (note) |
| Cellular Localization | Golgi apparatus membrane; Multi-pass membrane protein , Cell membrane; Multi-pass membrane protein |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
