Rabbit Polyclonal antibody to OCA2This gene encodes the human homolog of the mouse p (pink-eyed dilution) gene. The encoded protein is believed to be an integral membrane protein involved in small molecule transport, specifically tyrosine, which is a precursor to melanin synthesis. It is involved in mammalian pigmentation, where it may control skin color variation and act as a determinant of brown or blue eye color. Mutations in this gene result in type 2 oculocutaneous albinism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Immunogen
Recombinant protein of human OCA2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHC-PWB
WB 1:500 - 1:2000, IHC 1:50 - 1:200:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PED EYCL EYCL3 HCL3 oculocutaneous albinism II BOCA SHEP1 BEY1 BEY2 EYCL2 BEY P D15S12
Target
OCA2
Molecular Weight(MW)
93 kDa (note)
Application
Application
Western blot analysis of extracts of various cell lines, using OCA2 antibody.