| Product Name | OLR1 / LOX-1 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to LOX 1 (oxidized low density lipoprotein (lectin-like) receptor 1)This gene encodes a receptor protein which belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternative transcript variants have been described but their full-length sequence has not been determined. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human OLR1 / LOX-1. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Human |
| Predicted Reactivity | Rhesus MonkeyRhesus Monkey (91%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | CLEC8A antibody LOX1 antibody LOXIN antibody SCARE1 antibody SLOX1 antibody OLR1 antibody "scavenger receptor class E member 1 antibody" C-type lectin domain family 8 member A antibody hLOX-1 antibody oxidized low-density lipoprotein receptor 1 a |
|---|---|
| Molecular Weight(MW) | 31 kDa (note) (3) |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein , Secreted |
| Positive Control | A549 , HeLa , HepG2 , HCT116 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
