Application
Sample (50 ug of whole cell lysate) A: Rat bone marrow 12% SDS PAGE diluted at 1:500| Product Name | p19 INK4d antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to p19 INK4d (cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4))The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human p19 INK4d. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Species Reactivity | Rat |
| Predicted Reactivity | Human, Mouse, Rhesus Monkey, BovineHuman (100%), Mouse (88%), Rhesus Monkey (98%), Bovine (90%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | INK4D antibody p19 antibody p19-INK4D antibody CDKN2D antibody cyclin-dependent kinase 4 inhibitor D p19 antibody CDK inhibitor p19INK4d antibody "cell cycle inhibitor Nur77 associating protein antibody" cyclin-dependent kinase 4 inhibitor D antibo |
|---|---|
| Molecular Weight(MW) | 18 kDa (note) (2) |
Application
Sample (50 ug of whole cell lysate) A: Rat bone marrow 12% SDS PAGE diluted at 1:500| Positive Control | Rat bone marrow |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
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| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 40% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
