Rabbit polyclonal to MAPK11One of the major signaling pathways used by eukaryotic cells to translate extracellular signals into cellular responses is the MAP (mitogen-activated protein) kinase cascade. So far, four MAPK subgroups (ERK, ERK5, JNK and p38) have been identified in humans. p38 beta is closely related to p38. They differ, however, in that p38 is equally well activated by MKK (MAP kinase kinase) 3, MKK4, and MKK6, while p38 beta is preferentially activated by MKK6. p38 beta also shows a strong substrate preference to ATF2 (activating transcription factor 2).
Immunogen
This antibody was developed against a synthetic peptide of human MAPK11.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: Use at a concentration of 1 - 3 μg/ml. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouse
Concentration
0.5mg/ml
Purification
Protein G
Target Information
Gene Synonyms
P38B P38BETA2 PRKM11 SAPK2 SAPK2B p38-2 p38Beta
Target
MAPK11
Application
Application
Western blot analysis of MAPK11 in 15 ugs of (A) human brain and (B) mouse brain cell lysate at 2 ug/ml.
Positive Control
Human brain whole cell lysate.
Application Notes
WB: Use at a concentration of 1 - 3 μg/ml. Predicted molecular weight: 38 kDa. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.