Western blot analysis of RSK1 (pS380) expression in HeLa PMA-treated (A); A431 EGF-treated (B); NIH3T3 PMA-treated (C); PC12 PMA-treated (D) whole cell lysates.
Rabbit Polyclonal antibody to p90 RSK1 (phospho Ser380)This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RSK1. The exact sequence is proprietary.
Recognizes endogenous levels of RSK1 (pS380) protein.
Application
Application
Western blot analysis of RSK1 (pS380) expression in HeLa PMA-treated (A); A431 EGF-treated (B); NIH3T3 PMA-treated (C); PC12 PMA-treated (D) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.