Application
Western blot analysis of PAK2 (pS20) expression in HEK293T EGF-treated (A); Raw264.7 EGF-treated (B); H9C2 EGF-treated (C) whole cell lysates.| Product Name | PAK2 (phospho Ser20) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PAK2 (phospho Ser20)The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human PAK2. The exact sequence is proprietary. |
| Modification | p-Ser20 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PAK65 PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 PAKgamma |
|---|---|
| Target | PAK2 |
| Tissue Specificity | Recognizes endogenous levels of PAK2 (pS20) protein. |
Application
Western blot analysis of PAK2 (pS20) expression in HEK293T EGF-treated (A); Raw264.7 EGF-treated (B); H9C2 EGF-treated (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
