Rabbit Polyclonal antibody to PAR4Prostate apoptosis response protein (Par-4) is an ~38 kDa protein containing a leucine zipper at its carboxy terminus. The leucine zipper is required for Par-4 function during apoptosis and has also been shown to directly interact with Wilm’s Tumor Suppressor, WT-1. Par-4 is up-regulated in apoptotic prostate cells and has also been observed at ~18 times higher concentration in human brain tissue from Alzheimer's patients when compared to unaffected brain tissue.
Immunogen
Synthetic Peptide: C E(324) Q L K Q E N K T L L K V V G Q L T R(342)
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ICC/IFIHCIPWB
IHC: 1:1,000:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)