Rabbit Polyclonal antibody to PAX2PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide of human PAX2
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
ICC/IFWB
WB: 1:500 - 1:2000. IF: 1:50 - 1:200:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
PAPRS paired box 2
Target
PAX2
Molecular Weight(MW)
45 kDa (note)
Application
Application
WB analysis of extracts from various cells using PAX2 antibody.
Application
ICC/IF analysis of A549 cells using PAX2 antibody (green) and DAPI (blue).
Application Notes
WB: 1:500 - 1:2000. IF: 1:50 - 1:200:
Additional Information
Form
Liquid
Storage Instructions
Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.