Rabbit Polyclonal antibody to Paxillin (phospho Tyr118)This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011]
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human Paxillin (pY118). The exact sequence is proprietary.
Modification
p-Tyr118
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB: 1:500 - 1:1000:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
paxillin PXN
Target
Paxillin (phospho Tyr118)
Tissue Specificity
Recognizes endogenous levels of Paxillin (pY118) protein.
Application
Application
Western blot analysis of Paxillin (pY118) expression in A549 PDGF-treated (A); NIH3T3 PDGF-treated (B) whole cell lysates.
Application Notes
WB: 1:500 - 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Storage Buffer
Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.