| Product Name | PBG-D antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PBG-D (hydroxymethylbilane synthase)This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PBG-D. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Rat, Cat, Pig, Rhesus Monkey, BovineHuman (100%), Mouse (92%), Rat (92%), Cat (96%), Pig (95%), Rhesus Monkey (98%), Bovine (93%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PBG-D antibody PBGD antibody PORC antibody UPS antibody HMBS antibody porphobilinogen deaminase antibody "porphyria acute Chester type antibody" uroporphyrinogen I synthetase antibody uroporphyrinogen I synthase antibody pre-uroporphyrinogen sy |
|---|---|
| Target | PBG-D |
| Molecular Weight(MW) | 39 kDa (note) |
| Cellular Localization | Cytoplasm |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
