Application
Immunohistochemical analysis of paraffin-embedded U87 xenograft, using PDE11A antibody at 1:500 dilution.Application
Sample (30 ug of whole cell lysate) A: PC-3 7.5% SDS PAGE diluted at 1:1000| Product Name | PDE11A antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PDE11A (phosphodiesterase 11A)The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PDE11A. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| *Optimal dilutions/concentrations should be determined by the researcher.
: |
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| Species Reactivity | Human |
| Predicted Reactivity | Mouse, Rat, BovineMouse (99%), Rat (99%), Bovine (99%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | FLJ23693 antibody MGC133355 antibody MGC133356 antibody PPNAD2 antibody PDE11A antibody "dual 3' 5'-cyclic-AMP and -GMP phosphodiesterase 11A antibody" cAMP and cGMP cyclic nucleotide phosphodiesterase 11A antibody phosphodiesterase 11A antibody |
|---|---|
| Molecular Weight(MW) | 105 kDa (note) (4) |
| Cellular Localization | Cytoplasm , cytosol |
Application
Immunohistochemical analysis of paraffin-embedded U87 xenograft, using PDE11A antibody at 1:500 dilution.
Application
Sample (30 ug of whole cell lysate) A: PC-3 7.5% SDS PAGE diluted at 1:1000| Positive Control | PC-3 |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
