| Product Name | PDE4C antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to PDE4CCyclic nucleotides are hydrolyzed and compartmentalized by a family of enzymes called phosphodieterases. cAMP-specific phosphodiesterase type-4 (PDE4) family is comprised of 4 genes (PDE4 A, B, C and D) with multiple splice variants generated by RNA splicing and use of alternate initiation sites. The cAMP-dependent protein kinase A modulates the enzyme activity of some PDE4 family members by phosphorylation/dephosphorylation mechanisms. Such short-term regulatory mechanisms are necessary for rapid changes in the cAMP levels in cells. |
| Immunogen | Synthetic cyclic peptide (carboxy-terminal peptide common to all PDE4C proteins). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IPWB |
| IP: Use at a dilution of 1/20. WB: Use at a dilution of 1/500. Predicted molecular weight: 80 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|
| Species Reactivity | Human |
| Concentration | 0.5mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PDE4C-791 5143 Q08493 DPDE1 PDE4C791 PDE4C 600128 MGC126222 PDE4C 791 |
|---|---|
| Target | PDE4C |
| Tissue Specificity | This antibody detects 3 isoforms of PDE4C subclasses (PDE4C1, PDE4C2 and PDE4C3). |
| Application Notes | IP: Use at a dilution of 1/20. WB: Use at a dilution of 1/500. Predicted molecular weight: 80 kDa. Optimal dilutions/concentrations should be determined by the end user.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.02% Thimerosal / Merthiolate |
