Application
Western blot analysis of PDGFR beta (pY751) expression in THP1 EGF-treated (A); Raw264.7 EGF-treated (B); rat liver (C) whole cell lysates.| Product Name | PDGF Receptor beta (phospho Tyr751) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit Polyclonal antibody to PDGF Receptor beta (phospho Tyr751)This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PDGFR beta (pY751). The exact sequence is proprietary. |
| Modification | p-Tyr751 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB: 1:500 - 1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | PDGFR-1 PDGFR1 CD140B JTK12 PDGFRB PDGFR platelet-derived growth factor receptor beta polypeptide IBGC4 IMF1 |
|---|---|
| Target | PDGF Receptor beta |
| Tissue Specificity | Recognizes endogenous levels of PDGFR beta (pY751) protein. |
Application
Western blot analysis of PDGFR beta (pY751) expression in THP1 EGF-treated (A); Raw264.7 EGF-treated (B); rat liver (C) whole cell lysates.| Application Notes | WB: 1:500 - 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles. |
| Storage Buffer | Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. |
