| Product Name | PDK4 antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PDK4 (pyruvate dehydrogenase kinase, isozyme 4)This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin. [provided by RefSeq] |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human PDK4. The exact sequence is proprietary. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| *Optimal dilutions/concentrations should be determined by the researcher.
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| Predicted Reactivity | Human, Mouse, Rat, Pig, Chicken, Chimpanzee, BovineHuman (100%), Mouse (93%), Rat (93%), Pig (91%), Chicken (80%), Chimpanzee (99%), Bovine (90%) |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | FLJ40832 antibody PDK4 antibody "pyruvate dehydrogenase kinase isoenzyme 4 antibody" "pyruvate dehydrogenase lipoamide kinase isozyme 4 mitochondrial antibody" "pyruvate dehydrogenase kinase isozyme 4 antibody" "[Pyruvate dehydrogenase [lipoamide |
|---|---|
| Target | PDK4 |
| Molecular Weight(MW) | 46 kDa (note) |
| Cellular Localization | Mitochondrion matrix |
| Positive Control | Target recombinant protein |
|---|---|
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher.
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| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
