Rabbit Polyclonal antibody to PKC delta (protein kinase C, delta)Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]
Immunogen
Recombinant protein encompassing a sequence within the center region of human PKC delta. The exact sequence is proprietary.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
*Optimal dilutions/concentrations should be determined by the researcher.
Predicted Reactivity
Human, Mouse, Rat, Dog, Chicken, BovineHuman (100%), Mouse (93%), Rat (92%), Dog (92%), Chicken (84%), Bovine (90%)
Concentration
1mg/ml (Please refer to the vial label for the specific concentration)
Purification
Affinity purified
Target Information
Gene Synonyms
MGC49908 antibody, PKCD antibody, nPKC-delta antibody, PRKCD antibody, protein kinase C delta type antibody, protein kinase C delta VIII antibody, "protein kinase C, delta antibody"
Molecular Weight(MW)
78 kDa (note)
Cellular Localization
Cytoplasm (By similarity) , Membrane; Peripheral membrane protein
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.
Additional Information
Form
Liquid
Storage Instructions
Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.