| Product Name | PKC theta (phospho Thr219) antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal antibody to PKC theta-phospho T219 (protein kinase C, theta)Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq] |
| Modification | p-Thr219 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISA |
| *Optimal dilutions/concentrations should be determined by the researcher. | |
| Predicted Reactivity | Human, Mouse, Rat, Rhesus Monkey, BovineHuman (100%), Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%) |
| Concentration | 1mg/ml (Please refer to the vial label for the specific concentration) |
| Purification | Affinity purified |
| Gene Synonyms | MGC126514 antibody, MGC141919 antibody, PRKCT antibody, nPKC-theta antibody, PRKCQ antibody, protein kinase C theta type antibody, "protein kinase C, theta antibody", Phospho PKC theta (T219), Phospho PKC theta (pT219), Phospho PKC theta (Thr219), PKC thet |
|---|---|
| Target | PKC theta-phospho T219 |
| Molecular Weight(MW) | 82 kDa (note) |
| Application Notes | *Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative. |
