Rabbit polyclonal to PMS2This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq]
Immunogen
Synthetic peptide - Surrounding amino acid 864 of human PMS2
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
WB
For WB: Use at a contcentration of 0.5-4μg/ml. Based on ressearcher’s feedback the antibody also works well in IP and IHC, but has not yet been tested in house. Optimal dilutions/concentrations should be determined by the end user.:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
HNPCC4 PMS2CL PMSL2
Target
PMS2
Application Notes
For WB: Use at a contcentration of 0.5-4μg/ml. Based on ressearcher’s feedback the antibody also works well in IP and IHC, but has not yet been tested in house. Optimal dilutions/concentrations should be determined by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Upon Receipt - Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.