Rabbit polyclonal antibody to PPM1LActs as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
Immunogen
The antiserum was produced against synthesized peptide derived from human PPM1L.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.:
Species Reactivity
HumanMouse
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Gene Synonyms
Protein phosphatase 2C isoform epsilon EC 3.1.3.16 PPM1L Protein phosphatase1like Protein phosphatase 1like EC3.1.3.16 Protein phosphatase2C isoform epsilon Protein phosphatase 1-like PP2Cepsilon PP2C-epsilon PP2C epsilon Protein phosphatase 1 l
Target
PPM1L
Molecular Weight(MW)
41 kDa (note)
Tissue Specificity
PPM1L Antibody detects endogenous levels of total PPM1L protein.
Application
Application
Western blot analysis of extracts from Jurkat cells, using PPM1L Antibody. The lane on the right is treated with the synthesized peptide.
Application Notes
ELISA: 1:10000Optimal dilutions should be determined experimentally by the end user.:
Additional Information
Form
Liquid
Storage Instructions
Store at -20 degrees Celcius. Product is stable for at least 1 year.
Storage Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.