Application
Antibody used in WB on Human Lung at 0.2-1 ug/ml.| Product Name | ABCC1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ABCC1, ABC29, ABCC, DKFZp686N04233, DKFZp781G125, GS-X, MRP, MRP1 |
| Product description | ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.1) Nabekura, T., (2008) Biochem. Biophys. Res. Commun. 369 (2), 363-368. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ABCC1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| ABCC1 antibody can be used for detection of ABCC1 by ELISA at 1:62500. ABCC1 antibody can be used for detection of ABCC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | DogHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ABCC1 |
|---|---|
| Alternative Names | ABCC1 ABC29 ABCC DKFZp686N04233 DKFZp781G125 GS-X MRP MRP1 |
| Molecular Weight(MW) | 171 kDa |
Application
Antibody used in WB on Human Lung at 0.2-1 ug/ml.| Positive Control | 1) Cat. No. XBL-10410 - Fetal Lung Tissue Lysate |
|---|---|
| Application Notes | ABCC1 antibody can be used for detection of ABCC1 by ELISA at 1:62500. ABCC1 antibody can be used for detection of ABCC1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store ABCC1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
