Application
Western blot analysis of extract from HL-60 cells using ABCG2 (CD338) Antibody.| Product Name | ABCG2 (CD338) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, CD338, GOUT1, CDw338, UAQTL1, EST157481, MRX |
| Product description | Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.1) Henriksen U., Gether U., Litman T. J. Cell Sci. 118:1417-1426 (2005) Wakabayashi K., Nakagawa H., Tamura A., Koshiba S., Hoshijima K., Komada M., Ishikawa T. J. Biol. Chem. 282:27841-27846 (2007) |
| Immunogen | ABCG2 (CD338) antibody was raised against a peptide sequence around aa.160~164 ( R-I-N-R-V) derived from Human ABCG2 (CD338). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ABCG2 |
|---|---|
| Alternative Names | MRX MXR ABCP BCRP BMDP MXR1 ABC15 BCRP1 CD338 GOUT1 CDw338 UAQTL1 EST157481 MRX |
| Molecular Weight(MW) | 65 - 80 kDa |
| Tissue Specificity | This antibody detects endogenous level of total ABCG2(CD338) protein. |
| Entrez Gene | 9429 |
|---|---|
| Protein Accession | NP_004818.2 |
Application
Western blot analysis of extract from HL-60 cells using ABCG2 (CD338) Antibody.| Application Notes | Western Blot: 1:500: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
