ACTR2 is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion.The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene.1) Kim, D.J., (2006) J. Biol. Chem. 281 (1), 617-625.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACTR2.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAIHCWB
ACTR2 antibody can be used for detection of ACTR2 by ELISA at 1:1562500. ACTR2 antibody can be used for detection of ACTR2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Antibody used in WB on Human Jurkat cells at 2.5 ug/ml.
Application
Antibody used in IHC on Human Muscle.
Application Notes
ACTR2 antibody can be used for detection of ACTR2 by ELISA at 1:1562500. ACTR2 antibody can be used for detection of ACTR2 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store ACTR2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt