Application
Western blot analysis of lysed extracts from Rat and Mouse brain tissue using Adiponectin Antibody.| Product Name | Adiponectin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, ACDC |
| Product description | Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-κ-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.1) Yamauchi T., Kamon J., Waki H., Terauchi Y., Kubota N., Hara K., Mori Y., Ide T., Murakami K., Yoda M. Kadowaki T. Nat. Med. 7:941-946 (2001) Richards A. A., Stephens T., Charlton H. K., Jones A., Macdonald G. A., Prins J. B., Whitehead J. P. Mol. Endocrinol. 20:1673-1687 (2006) |
| Immunogen | Adiponectin antibody was raised against a peptide sequence around aa.235~239 (T-G-F-L-L) derived from Human Adiponectin. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ADIPOQ |
|---|---|
| Alternative Names | ACDC ADPN APM1 APM-1 GBP28 ACRP30 ADIPQTL1 ACDC |
| Molecular Weight(MW) | 27 kDa |
| Tissue Specificity | This antibody detects endogenous level of total Adiponectin protein. |
| Entrez Gene | 9370 |
|---|---|
| Protein Accession | NP_001171271.1 |
Application
Western blot analysis of lysed extracts from Rat and Mouse brain tissue using Adiponectin Antibody.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
