Vasoactive intestinal peptide is a neuroprotective factor
that has a stimulatory effect on the growth of some tumor cells and
an inhibitory effect on others. This gene encodes a protein that is
upregulated by vasoactive intestinal peptide and may be involved in
its stimulatory effect on certain tumor cells. The encoded protein
contains one homeobox and nine zinc finger domains, suggesting that
it functions as a transcription factor. This gene is also
upregulated in normal proliferative tissues. Finally, the encoded
protein may increase the viability of certain cell types through
modulation of p53 activity. Alternatively spliced transcript
variants encoding the same protein have been described. [provided
by RefSeq].1) Braitch, M., et al. Neuroimmunomodulation 17(2):120-125(2010)
Immunogen
This ADNP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 831-860 amino acids from the C-terminal region of human ADNP.
Western Blot at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 ug per lane.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.