Application
Antibody is used in Western blot to detect GRK3 in mouse heart tissue lysate.| Product Name | AD_K2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Beta-adrenergic receptor kinase 2, Beta-ARK-2, G-protein-coupled receptor kinase 3, ADRBK2, BARK2, GRK3 |
| Product description | The beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.1) Calabrese, G., et al., Genomics 23(1):286-288 (1994). Parruti, G., et al., Biochem. Biophys. Res. Commun. 190(2):475-481 (1993). Benovic, J.L., et al., J. Biol. Chem. 266(23):14939-14946 (1991). |
| Immunogen | This AD_K2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 633-660 amino acids from the C-terminal region of human AD_K2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | HumanMonkeyMouse |
| Concentration | 1mg/ml |
| Gene Symbol | ADRBK2 |
|---|---|
| Alternative Names | Beta-adrenergic receptor kinase 2 Beta-ARK-2 G-protein-coupled receptor kinase 3 ADRBK2 BARK2 GRK3 |
| Molecular Weight(MW) | 80 kDa |
Application
Antibody is used in Western blot to detect GRK3 in mouse heart tissue lysate.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
