This gene encodes a putative transcriptional activator
that is a member of the AF4FMR2 gene family. This gene is
associated with the folate-sensitive fragile X E locus on
chromosome X. A repeat polymorphism in the fragile X E locus
results in silencing of this gene causing Fragile X E syndrome.
Fragile X E syndrome is a form of nonsyndromic X-linked mental
retardation. Alternate splicing results in multiple transcript
variants.1) Bensaid, M., et al. Nucleic Acids Res. 37(4):1269-1279(2009)
Immunogen
This AFF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 886-912 amino acids from the Central region of human AFF2.
AF4/FMR2 family member 2 Fragile X E mental retardation syndrome protein Fragile X mental retardation 2 protein FMR2P Protein FMR-2 Protein Ox19 AFF2 FMR2 OX19
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.