Application
Antibody used in IHC on Human Lung at 4.0-8.0 ug/ml.Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Product Name | AGER Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms.This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms.1) Takahashi, K., (2006) Thromb. Haemost. 95 (2), 320-328. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AGER. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| AGER antibody can be used for detection of AGER by ELISA at 1:62500. AGER antibody can be used for detection of AGER by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AGER |
|---|---|
| Alternative Names | AGER MGC22357 RAGE |
| Molecular Weight(MW) | 38 kDa |
Application
Antibody used in IHC on Human Lung at 4.0-8.0 ug/ml.
Application
Antibody used in WB on Human HepG2 at 0.2-1 ug/ml.| Application Notes | AGER antibody can be used for detection of AGER by ELISA at 1:62500. AGER antibody can be used for detection of AGER by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store AGER antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL. |
