Application
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Product Name | ALAS2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ALAS2, ANH1, ASB, PRO2399, XLSA, ALASE, XLDPP, XLEPP, ALAS-E |
| Product description | ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.1) Astner, I., (2005) EMBO J. 24 (18), 3166-3177. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ALAS2. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| ALAS2 antibody can be used for detection of ALAS2 by ELISA at 1:62500. ALAS2 antibody can be used for detection of ALAS2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | ALAS2 |
|---|---|
| Alternative Names | ALAS2 ANH1 ASB PRO2399 XLSA ALASE XLDPP XLEPP ALAS-E |
| Molecular Weight(MW) | 57 kDa, 65 kDa, 61 kDa, 63 kDa |
| Entrez Gene | 212 |
|---|---|
| Protein Accession | NP_001033058 |
Application
Antibody used in IHC on Human Kidney at 4.0-8.0 ug/ml.
Application
Antibody used in WB on Human Jurkat 5.0 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | ALAS2 antibody can be used for detection of ALAS2 by ELISA at 1:62500. ALAS2 antibody can be used for detection of ALAS2 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store ALAS2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
