Application
Antibody used in IHC on Human kidney.Application
Antibody used in WB on Human NCI-H226 at 2.5 ug/ml.| Product Name | APTX Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | APTX, AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT |
| Product description | APTX is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. APTX may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.This gene encodes a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. The encoded protein may play a role in single-stranded DNA repair. Mutations in this gene have been associated with ataxia-ocular apraxia. Multiple transcript variants encoding distinct isoforms have been identified for this gene, however, the full length nature of some variants has not been determined.1) Ahnesorg, P., (2006) Cell 124 (2), 301-313. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human APTX. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCWB |
| APTX antibody can be used for detection of APTX by ELISA at 1:1562500. APTX antibody can be used for detection of APTX by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | APTX |
|---|---|
| Alternative Names | APTX AOA AOA1 AXA1 EAOH EOAHA FHA-HIT |
| Molecular Weight(MW) | 38 kDa, 20 kDa, 20 kDa, 29 kDa |
Application
Antibody used in IHC on Human kidney.
Application
Antibody used in WB on Human NCI-H226 at 2.5 ug/ml.| Positive Control | 1) NCI-H226 Cell Lysate |
|---|---|
| Application Notes | APTX antibody can be used for detection of APTX by ELISA at 1:1562500. APTX antibody can be used for detection of APTX by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store APTX antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
