Aquaporin 3 is a water channel protein. Aquaporins are a
family of small integral membrane proteins related to the major
intrinsic protein (MIP or AQP0). Aquaporin 3 is localized at the
basal lateral membranes of collecting duct cells in the kidney. In
addition to its water channel function, aquaporin 3 has been found
to facilitate the transport of nonionic small solutes such as urea
and glycerol, but to a smaller degree. It has been suggested that
water channels can be functionally heterogeneous and possess water
and solute permeation mechanisms.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This AQP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the Central region of human AQP3.
Western blot analysis in mouse kidney tissue lysates (35ug/lane).
Application
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.