Application
Staining of Peroxiredoxin 2 in TSU PR1 cells using| Product Name | PRX II antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Rabbit polyclonal to Peroxiredoxin 2The Peroxiredoxin (Prdx, Prx, or Trx-Px) family of enzymes is a recently identified family of peroxidases found in free-living organisms. The six known isoforms (Prx1-6) play an important role in protecting lipids, enzymes and DNA against peroxides, such as hydrogen peroxide. The ubiquitously expressed peroxiredoxins have also been shown to play a role in apoptosis and cell differentiation. This is acomplished by the active cysteine of Prx reducing peroxides, which is then converted into a transient cysteine sulfenic acid or cysteine sulfinic acid. If Prx protection is inadequate against peroxidases, the resulting protein and DNA damage may result in neurological disease such as Alzheimer's or DNA damage leading to cancer. |
| Immunogen | Synthetic peptide: LLADVTRRLSED, corresponding to amino acids 104-115 of Human Peroxiredoxin 2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ICC/IFIHCWB |
| ICC/IF: 1:500: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Synonyms | Peroxiredoxin2 Peroxiredoxin 2 MGC4104 NKEFB PRP PRX2 PRXII TDPX1 TPX1 TSA |
|---|---|
| Target | Peroxiredoxin 2 |
| Cellular Localization | Cytoplasmic |
Application
Staining of Peroxiredoxin 2 in TSU PR1 cells using| Positive Control | TSU PR1 cells (ICC)PC3 cell lysate (WB) |
|---|---|
| Application Notes | ICC/IF: 1:500: |
| Form | Liquid |
|---|---|
| Storage Instructions | Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles. |
| Storage Buffer | Preservative: 0.05% Sodium Azide |
