Application
Immunohistochemistry staining of Aurora Kinase B in tonsil tissue using Aurora Kinase B Antibody.| Product Name | Aurora Kinase B (phospho Thr232) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | AURKB, AIRK2, AIK2, Aurora kinase B, Aurora kinase B-Sv1, Aurora-related kinase 2, Aurora/IPL1-related kinase 2, ARK-2, ARK2, Aurkb-sv1, Aurkb-sv2, Aurora 1, Aurora-B, AIM-1, IPL1, STK-1, STK5, PPP1R48, AurB, Aurora B, Aurora kinase B-Sv2, Aurora-1, Aurora |
| Product description | Aurora Kinase B (also known as Aurora and Ipl1-like midbody-associated protein 1, AIM-1, Aurora/IPL1-related kinase 2, Aurora-related kinase 2, STK-1, and Aurora-B) is a Ser/Thr protein kinase member of the Aurora subfamily that may be directly involved in regulating the cleavage of polar spindle microtubules and is a key regulator for the onset of cytokinesis during mitosis. Aurora Kinase B is localized to the midzone of central spindle in late anaphase and concentrated into the midbody in telophase and cytokinesis and is colocalized with gamma tubulin in the mid-body. High levels of Aurora B expression are seen in the thymus, although it is also expressed in the spleen, lung, testis, colon, placenta and fetal liver. Aurora B is expressed during S and G2/M phase and expression is up-regulated in cancer cells during M phase. |
| Immunogen | Aurora Kinase B antibody was raised against phospho amino acids 223 - 234 of Aurora Kinase B (Human). |
| Modification | p-Thr232 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHCWB |
| Aurora Kinase B antibody can be used in ELISA starting at 1:6000 - 1:30000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1.25 μg/mL.: |
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| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | AURKB |
|---|---|
| Alternative Names | AURKB AIRK2 AIK2 Aurora kinase B Aurora kinase B-Sv1 Aurora-related kinase 2 Aurora/IPL1-related kinase 2 ARK-2 ARK2 Aurkb-sv1 Aurkb-sv2 Aurora 1 Aurora-B AIM-1 IPL1 STK-1 STK5 PPP1R48 AurB Aurora B Aurora kinase B-Sv2 Aurora-1 Aurora |
| Tissue Specificity | pThr232 |
Application
Immunohistochemistry staining of Aurora Kinase B in tonsil tissue using Aurora Kinase B Antibody.| Application Notes | Aurora Kinase B antibody can be used in ELISA starting at 1:6000 - 1:30000, Western Blot starting at 1:500 - 1:2000, and immunohistochemistry starting at 1.25 μg/mL.: |
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| Form | Liquid |
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| Storage Instructions | Store Aurora Kinase B antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
