Application
Hemagglutinin antibody at 1 μg/mL specifically recognizes Avian H5N1 influenza virus but not seasonal influenza virus A H1N1 Hemagglutinin protein.Application
Western blot analysis of (A) 5 ng and (B) 25 ng of recombinant HA1 with Avian Influenza Hemagglutinin antibody at 1 μg/mL.| Product Name | Avian Influenza Hemagglutinin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Avian Influenza Hemagglutinin Antibody: |
| Product description | Avian Influenza Hemagglutinin Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.1) Thompson WW, Shay DK, Weintraub, et al. Mortality associated with influenza and respiratory syncytial virus in the United States. JAMA 2003; 289:179-186. |
| Immunogen | Avian influenza hemagglutinin antibody was raised against a synthetic peptide corresponding to 15 amino acids at the amino terminus of the avian influenza hemagglutinin protein. Efforts were made to use relatively conserved regions of the viral sequence as |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| Avian influenza hemagglutinin antibody can be used for the detection of the avian influenza hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μg/mL. Antibody can also be used in western blot applications.: |
|
| Species Reactivity | Virus |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NA |
|---|---|
| Alternative Names | Avian Influenza Hemagglutinin Antibody: |
| Protein Accession | AAT76166 |
|---|
Application
Hemagglutinin antibody at 1 μg/mL specifically recognizes Avian H5N1 influenza virus but not seasonal influenza virus A H1N1 Hemagglutinin protein.
Application
Western blot analysis of (A) 5 ng and (B) 25 ng of recombinant HA1 with Avian Influenza Hemagglutinin antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 95-101 - H5 Hemagglutinin HA1 Recombinant Protein |
|---|---|
| Application Notes | Avian influenza hemagglutinin antibody can be used for the detection of the avian influenza hemagglutinin protein from the H5N1 strain of avian influenza A in ELISA. It will detect 10 ng of free peptide at 1 μg/mL. Antibody can also be used in western blot applications.: |
| Form | Liquid |
|---|---|
| Storage Instructions | Avian Influenza Hemagglutinin antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Avian Influenza Hemagglutinin Antibody is supplied in PBS containing 0.02% sodium azide. |
