Application
Immunofluorescence staining of methanol-fixed A549 cells using Bax (Phospho-Thr167) Antibody.| Product Name | Bax (phospho Thr167) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.1) Francesca Andriani. J Natl Cancer Inst, Sep 2001; 93: 1314 - 1324. |
| Immunogen | Bax (phospho Thr167) antibody was raised against a peptide sequence around phosphorylation site of threonine167 (P-G-T (p)-P-T) derived from Human Bax. |
| Modification | p-Thr167 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IF |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BAX |
|---|---|
| Alternative Names | BAXA Apoptosis regulator BAX membrane isoform alpha Bcl2-associated X protein |
| Molecular Weight(MW) | 21 kDa |
| Tissue Specificity | The antibody detects endogenous levels of Bax only when phosphorylated at threonine 167. |
| Entrez Gene | 581 |
|---|---|
| Protein Accession | NP_620116.1 |
Application
Immunofluorescence staining of methanol-fixed A549 cells using Bax (Phospho-Thr167) Antibody.| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
